Last most-relevant publications
- Splice variants of mitofusin 2 shape the endoplasmic reticulum and tether it to mitochondria Science
- Correlated motions in DNA: beyond base-pair step models of DNA flexibility Nucleic Acids Research
- Controlled sulfur-based engineering confers mouldability to phosphorothioate antisense oligonucleotides Nucleic Acids Research
- Characterization of p38α autophosphorylation inhibitors that target the non-canonical activation pathway Nature Communications
Prediction and validation of protein intermediate states from structurally rich ensembles and coarse-grained simulations
Multiscale simulation of DNA
DNA is not only among the most important molecules in life, but a meeting point for biology, physics and chemistry, being studied by numerous techniques. Theoretical methods can help in gaining a detailed understanding of DNA structure and function, but their practical use is hampered by the multiscale nature of this molecule.